MEK2 antibody (AA 350-400)

Catalog No. ABIN7452366

The Rabbit Polyclonal anti-MEK2 antibody (ABIN7452366) specifically detects MEK2 in IP. The antibody is reactive with Human samples.

Quick Overview for MEK2 antibody (AA 350-400) (ABIN7452366)

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEK2 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-MEK2 Antibody

Binding Specificity: AA 350-400

Purpose: Rabbit anti-MEK2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 350 and 400

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-MEK2 antibody ABIN7453730.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MEK2

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Alternative Name: MEK2

Background: Background: MEK2 (MAP2K2) is a dual specificity protein kinase that belongs to the MAP kinase kinase family. MEK2 is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3, and is involved in a multitude of cellular processes such as proliferation, differentiation, gene activation, and development [taken from NCBI Entrez Gene (Gene ID: 5605)].

Gene ID: 5605

NCBI Accession: NP_109587

UniProt: P36507

Pathways: MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling