POLH antibody (AA 640-690)
Quick Overview for POLH antibody (AA 640-690) (ABIN7452399)
Target
See all POLH AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 640-690
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Purpose
- Rabbit anti-PolH Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 640 and 690
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-PolH antibody ABIN7450582.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- POLH (Polymerase (DNA Directed), eta (POLH))
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Alternative Name
- PolH
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Background
- Background: PolH is a DNA polymerase specifically involved in DNA repair and somatic hypermutation. Defects in PolH result in a variant type of xeroderma pigmentosum, a disease characterized by sunlight hypersensitivity, increased incidence of cancer, and neurological abnormalities.
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Gene ID
- 5429
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NCBI Accession
- NP_006493
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UniProt
- Q9Y253
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Pathways
- DNA Damage Repair
Target
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