PAM antibody (AA 2425-2475)

Catalog No. ABIN7452920

Product Details anti-PAM Antibody

Target: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Binding Specificity: AA 2425-2475

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAM antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-PAM Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 2425 and 2475

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAM

Target: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Alternative Name: PAM (PAM Products)

Synonyms: PAL antibody, PHM antibody, pal antibody, phm antibody, pamb antibody, CG3832 antibody, Dmel\\CG3832 antibody, dPHM antibody, AE-I antibody, PAL-A antibody, PHM-A antibody, pama antibody, si:dkeyp-35f12.2 antibody, peptidylglycine alpha-amidating monooxygenase antibody, peptidylglycine alpha-amidating monooxygenase S homeolog antibody, Peptidylglycine-alpha-hydroxylating monooxygenase antibody, peptidylglycine alpha-amidating monooxygenase L homeolog antibody, PAM antibody, Pam antibody, pam.S antibody, CHLREDRAFT_150435 antibody, sce7070 antibody, pam antibody, Phm antibody, pam.L antibody

Background: Background: In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway.

Gene ID: 23077

NCBI Accession: NP_055872

UniProt: O75592