PSMD12 antibody (AA 1-50)

Catalog No. ABIN7452964

Product Details anti-PSMD12 Antibody

Target: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD12 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-PSMD12 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Bovine,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PSMD12

Target: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Alternative Name: PSMD12 (PSMD12 Products)

Synonyms: wu:fb38a06 antibody, wu:fc34f08 antibody, wu:fc49f02 antibody, PSMD12 antibody, rpn5 antibody, Rpn5 antibody, p55 antibody, 1500002F15Rik antibody, AI480719 antibody, P55 antibody, proteasome 26S subunit, non-ATPase 12 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 antibody, psmd12 antibody, PSMD12 antibody, Psmd12 antibody

Background: Background: Proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (PSMD12) is a subunit of the 26S proteasome, a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD12 is a non-ATPase subunit of the 19S regulator. [taken from NCBI Entrez Gene (Gene ID: 5718)].

Gene ID: 5718

NCBI Accession: NP_002807

UniProt: O00232

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway