CHD7 antibody (AA 2947-2997)

Catalog No. ABIN7453314

The Rabbit Polyclonal anti-CHD7 antibody (ABIN7453314) specifically detects CHD7 in WB and IP. The antibody is reactive with Human samples.

Quick Overview for CHD7 antibody (AA 2947-2997) (ABIN7453314)

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD7 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CHD7 Antibody

Binding Specificity: AA 2947-2997

Purpose: Rabbit anti-CHD7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 2947 and 2997

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CHD7

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Alternative Name: CHD7

Background: Background: CHD7 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD7 is implicated to play a role in development. Mutations in CHD7 are associated with CHARGE syndrome, a multi-symptom syndrome characterized by congenital anomalies and malformations of the heart, inner ear, retina, and palate.

Gene ID: 55636

NCBI Accession: NP_060250

UniProt: Q9P2D1

Pathways: Sensory Perception of Sound, Chromatin Binding