INSIG2 antibody (AA 65-160) (HRP)

Catalog No. ABIN719045

The Rabbit Polyclonal anti-INSIG2 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect INSIG2 in samples from Mouse.

Quick Overview for INSIG2 antibody (AA 65-160) (HRP) (ABIN719045)

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSIG2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-INSIG2 Antibody (HRP)

Binding Specificity: AA 65-160

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Insig2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for INSIG2

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Alternative Name: Insig2

Background:

Synonyms: Hypothetical protein INSIG2, INSIG 2, INSIG-2, INSIG 2 membrane protein, INSIG2 membrane protein, Insulin induced gene 2, Insulin induced gene 2 protein, Insulin induced protein 2, MGC26273, INSI2_HUMAN.

Background: Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Gene ID: 51141

Pathways: ER-Nucleus Signaling