CRTC2 antibody (AA 300-350)

Catalog No. ABIN7454370

This Rabbit Polyclonal antibody specifically detects CRTC2 in IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for CRTC2 antibody (AA 300-350) (ABIN7454370)

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC2 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CRTC2 Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-TORC2 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-TORC2 antibody A300-638A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CRTC2

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Alternative Name: TORC2

Background: Background: TORC2 (transducer of regulated CREB activity 2) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC1 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. TORC2 has been found to be pivotal to the process of gluconeogenesis.

Gene ID: 200186

NCBI Accession: NP_859066

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis