POLL antibody (AA 525-575)

Catalog No. ABIN7454415

This Rabbit Polyclonal antibody specifically detects POLL in IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for POLL antibody (AA 525-575) (ABIN7454415)

Target: POLL (Polymerase (DNA Directed), lambda (POLL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLL antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-POLL Antibody

Binding Specificity: AA 525-575

Purpose: Rabbit anti-Pol Lambda Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 525 and 575

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-Pol Lambda antibody A301-640A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for POLL

Target: POLL (Polymerase (DNA Directed), lambda (POLL))

Alternative Name: Pol Lambda

Background: Background: DNA polymerase lambda (pol lambda) is a DNA polymerase involved in base excision repair (BER). Pol lambda possesses terminal transferase and 5'-deoxyribose-5-phosphate lyase activity. These activities have been found to be coordinated by PCNA and replication protein A.

Gene ID: 27343

NCBI Accession: NP_037406

UniProt: Q9UGP5

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response