EFTUD2 antibody (AA 1-50)

Catalog No. ABIN7454700

Product Details anti-EFTUD2 Antibody

Target: EFTUD2 (Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2))

Binding Specificity: AA 1-50

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFTUD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-EFTUD2/SNRP116 Antibody, Affinity Purified

Predicted Reactivity: Chicken,Bovine,Orangutan

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EFTUD2

Target: EFTUD2 (Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2))

Alternative Name: EFTUD2/SNRP116 (EFTUD2 Products)

Synonyms: snrp116 antibody, snu114 antibody, wu:fi20f05 antibody, zgc:66214 antibody, U5-116KD antibody, SNRP116 antibody, MFDGA antibody, MFDM antibody, SNRNP116 antibody, Snrp116 antibody, Snu114 antibody, 116kDa antibody, U5-116kD antibody, elongation factor Tu GTP binding domain containing 2 S homeolog antibody, elongation factor Tu GTP binding domain containing 2 antibody, eftud2.S antibody, eftud2 antibody, EFTUD2 antibody, CpipJ_CPIJ011675 antibody, CpipJ_CPIJ016234 antibody, Eftud2 antibody

Background: Background: The splicesome is the molecular machine responsible for catalyzing intron removal from pre-mRNA transcripts. The splicesome is composed of several small nuclear RNAs (snRNAs) complexed with their associated proteins [together termed snRNPs (small nuclear ribonucleoprotein)]. One of the major classes of snRNPs includes the U1, U2, U4, U5 and U6 snRNP. EFTUD2/SNRP116 is a component of the U5 snRNP. EFTUD2/SNRP116 is a GTPase that may play a role in disrupting U4/U6 helices prior to splicesome activation.

Gene ID: 9343

NCBI Accession: NP_004238

UniProt: Q15029