Recombinant CD226 antibody (AA 19-229)

Catalog No. ABIN7455092

This anti-CD226 antibody is a Rabbit Monoclonal antibody detecting CD226 in WB, IP, ICC and IHC (fp). Suitable for Human.

Quick Overview for Recombinant CD226 antibody (AA 19-229) (ABIN7455092)

Target: CD226

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD226 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BLR063G

Product Details anti-CD226 Antibody

Binding Specificity: AA 19-229

Purpose: Rabbit anti-DNAM-1/CD226 Recombinant Monoclonal Antibody [BLR063G]

Immunogen: residues 19-229 (ECD)

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD226

Target: CD226

Alternative Name: DNAM-1/CD226

Background: Background: DNAX accessory molecule-1 (DNAM-1) is a receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell [taken from the Universal Protein Resource (UniProt) Q15762].

Gene ID: 10666

NCBI Accession: NP_006557

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints