Recombinant IFNAR1 antibody

Catalog No. ABIN7490524

The Human Chimeric anti-IFNAR1 antibody is suitable to detect IFNAR1 in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for Recombinant IFNAR1 antibody (ABIN7490524)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Antibody Type: Recombinant Antibody

Fragment: Fc fragment

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This IFNAR1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: DMC221

Product Details anti-IFNAR1 Antibody

Purpose: Anti-IFNAR1 antibody(DMC221), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Alternative Name: IFNAR1

Background: Interferon alpha/beta receptor 1,IFN-R-1,IFN-alpha/beta receptor 1,CRF2-1,Type I interferon receptor 1
Description: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.

UniProt: P17181

Pathways: JAK-STAT Signaling, Hepatitis C