KLRG1 antibody (FITC)
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- Target See all KLRG1 Antibodies
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
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Reactivity
- Human
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Host
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Golden Syrian Hamster
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Clonality
- Monoclonal
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Conjugate
- This KLRG1 antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Clone
- 2F1
- Isotype
- IgG
- Top Product
- Discover our top product KLRG1 Primary Antibody
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- Application Notes
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
- Comment
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Matching Isotype Control: FITC Syrian Hamster IgG Isotype Control (ABIN7469730)
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Target
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
- Alternative Name
- KLRG-1 (KLRG1 Products)
- Synonyms
- KLRG1 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, 2F1 antibody, CLEC15A antibody, MAFA-2F1 antibody, MAFA-LIKE antibody, killer cell lectin like receptor G1 antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, KLRG1 antibody, Klrg1 antibody
- Background
- MAFA, 2F20-Ag,Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG20 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.
- Gene ID
- 10219, 50928
- UniProt
- Q96E93, O88713
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