Integrin beta 2 antibody (PE-Cy7)

Catalog No. ABIN7457562

This Rat Monoclonal antibody specifically detects Integrin beta 2 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for Integrin beta 2 antibody (PE-Cy7) (ABIN7457562)

Target: Integrin beta 2 (ITGB2)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Clone: M18-2

Product Details anti-Integrin beta 2 Antibody (PE-Cy7)

Isotype: IgG2a, kappa

Application Details

Application Notes: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Comment:

Matching Isotype Control: PE/Cyanine7 Rat IgG2a, κ Isotype Control (ABIN7469844)

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Background: Integrin beta-2,Itgb2,Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta,Complement receptor C3 subunit beta,CD18,CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.

Gene ID: 16414

UniProt: P11835

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation