T-Box 5 antibody

Catalog No. ABIN7464506

Product Details anti-T-Box 5 Antibody

Target: T-Box 5 (TBX5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Rat, Zebrafish (Danio rerio)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TBX5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa nuclear extract

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.31 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for T-Box 5

Target: T-Box 5 (TBX5)

Alternative Name: T-box 5 (TBX5 Products)

Synonyms: TBX5 antibody, tbx-5 antibody, xtbx-5 antibody, xtbx5 antibody, tbx5 antibody, HOS antibody, tbx5.1 antibody, zTbx5 antibody, zf-tbx5 antibody, T-box 5 antibody, T-box 5 L homeolog antibody, T-box 5a antibody, TBX5 antibody, tbx5 antibody, tbx5.L antibody, Tbx5 antibody, tbx5a antibody

Background: T-box 5 , HOS,This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Molecular Weight: 58 kDa

Gene ID: 6910

UniProt: Q99593