Emerin antibody (AA 25-125) (Cy5)
-
- Target See all Emerin (EMD) Antibodies
- Emerin (EMD)
-
Binding Specificity
- AA 25-125
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Emerin antibody is conjugated to Cy5
-
Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Emerin
- Isotype
- IgG
- Top Product
- Discover our top product EMD Primary Antibody
-
-
- Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Emerin (EMD)
- Alternative Name
- Emerin (EMD Products)
- Synonyms
- fj58f01 antibody, wu:fj58f01 antibody, EMD antibody, Bocks antibody, Bocksbeutel antibody, CG9424 antibody, Dmel\\CG9424 antibody, emerin antibody, emd antibody, xemd1 antibody, xemerin2 antibody, xemd2 antibody, xemerin1 antibody, EDMD antibody, LEMD5 antibody, STA antibody, AW550900 antibody, Sta antibody, emerin antibody, emerin (Emery-Dreifuss muscular dystrophy) antibody, bocksbeutel antibody, emerin L homeolog antibody, emerin S homeolog antibody, EMD antibody, emd antibody, bocks antibody, emd.L antibody, emd.S antibody, Emd antibody
- Background
-
Synonyms: EDMD, EMD, EMD_HUMAN, Emerin, Emery Dreuss muscular dystrophy, STA.
Background: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.Tissue specificity, Skeletal muscle, heart, colon, testis, ovary and pancreas.
- Gene ID
- 2010
-