FOXO1 antibody (AA 242-655)
Quick Overview for FOXO1 antibody (AA 242-655) (ABIN7465657)
Target
See all FOXO1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 242-655
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Cross-Reactivity
- Human
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Purification
- Protein G purified
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Immunogen
- Amino acids 242-655 of FKHR expressed in E. coli.
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Isotype
- IgG2b
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Application Notes
- WB: 0.1 - 2 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: Cos 1 cells transfected with human FKHR
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, No Preservative
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Preservative
- Without preservative
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- FOXO1 (Forkhead Box O1 (FOXO1))
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Alternative Name
- forkhead box O1
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Background
- Forkhead box O1 , FKH1 , FKHR , FOXO1A,This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]
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Molecular Weight
- 70 kDa
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Gene ID
- 2308
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UniProt
- Q12778
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Pathways
- PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
Target
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