FOXO1 antibody (AA 242-655)

Catalog No. ABIN7465658

This anti-FOXO1 antibody is a Mouse Monoclonal antibody detecting FOXO1 in WB and IHC. Suitable for Human.

Quick Overview for FOXO1 antibody (AA 242-655) (ABIN7465658)

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 4-00E-07

Product Details anti-FOXO1 Antibody

Binding Specificity: AA 242-655

Cross-Reactivity: Human

Purification: Protein G purified

Immunogen: Amino acids 242-655 of FKHR expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: WB: 0.1 - 2 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Cos 1 cells transfected with human FKHR

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Alternative Name: forkhead box O1

Background: Forkhead box O1 , FKH1 , FKHR , FOXO1A,This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]

Molecular Weight: 70 kDa

Gene ID: 2308

UniProt: Q12778

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling