CYP2C8 antibody

Catalog No. ABIN7468190

Product Details anti-CYP2C8 Antibody

Target: CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2C8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CYP2C8. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CYP2C8

Target: CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Alternative Name: cytochrome P450 family 2 subfamily C member 8 (CYP2C8 Products)

Synonyms: CPC8 antibody, CYPIIC8 antibody, MP-12/MP-20 antibody, CYP2C74 antibody, cpc8 antibody, cyp2c8 antibody, cypiic8 antibody, mp-12/mp-20 antibody, cytochrome P450 family 2 subfamily C member 8 antibody, Cytochrome P450 2C8 antibody, cytochrome P450, family 2, subfamily C, polypeptide 8 antibody, cytochrome P450 family 2 subfamily C member 8 S homeolog antibody, CYP2C8 antibody, CTN_0597 antibody, cyp2c8.1.S antibody, cyp2c8.1 antibody

Background:

Synonyms: cytochrome P450 family 2 subfamily C member 8 , CPC8 , CYP2C8DM , CYPIIC8 , MP-12/MP-20

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq]

Molecular Weight: 56 kDa

Gene ID: 1558

UniProt: P10632