KLRC2 antibody (N-Term)
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- Target See all KLRC2 Antibodies
- KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))
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Binding Specificity
- N-Term
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KLRC2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human NKG2C. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product KLRC2 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: K562
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.56 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))
- Alternative Name
- killer cell lectin like receptor C2 (KLRC2 Products)
- Synonyms
- CD159c antibody, NKG2-C antibody, NKG2C antibody, killer cell lectin like receptor C2 antibody, killer cell lectin-like receptor subfamily C, member 2 antibody, KLRC2 antibody
- Background
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Synonyms: killer cell lectin like receptor C2 , CD159c , NKG2-C , NKG2C
Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
- Molecular Weight
- 26 kDa
- Gene ID
- 3822
- UniProt
- P26717
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