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SWAP70 antibody (N-Term)

This anti-SWAP70 antibody is a Rabbit Polyclonal antibody detecting SWAP70 in WB. Suitable for Human.
Catalog No. ABIN7469042

Quick Overview for SWAP70 antibody (N-Term) (ABIN7469042)

Target

See all SWAP70 Antibodies
SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Reactivity

  • 68
  • 11
  • 8
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Host

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  • 1
Rabbit

Clonality

  • 53
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Polyclonal

Conjugate

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  • 2
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SWAP70 antibody is un-conjugated

Application

  • 56
  • 29
  • 13
  • 13
  • 6
  • 6
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  • 2
  • 1
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Western Blotting (WB)
  • Binding Specificity

    • 15
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    N-Term

    Cross-Reactivity

    Human

    Purification

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the N-terminus region of human SWAP70. The exact sequence is proprietary.

    Isotype

    IgG
  • Application Notes

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Comment

    Positive Control: 293T , A431 , HeLa , HepG2 , Raji

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.7 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    Preservative

    Thimerosal (Merthiolate)

    Precaution of Use

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

    Alternative Name

    switching B cell complex subunit SWAP70

    Background

    Synonyms: switching B cell complex subunit SWAP70 , HSPC321 , SWAP-70

    Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

    Molecular Weight

    69 kDa

    Gene ID

    23075

    UniProt

    Q9UH65

    Pathways

    Production of Molecular Mediator of Immune Response
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