SWAP70 antibody (C-Term)
Quick Overview for SWAP70 antibody (C-Term) (ABIN7469043)
Target
See all SWAP70 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Cross-Reactivity
- Human, Mouse
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human SWAP70. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: Jurkat , Raji , NCI-H929 , 293T , A431 , HeLa , HepG2 Validation: Comparison
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
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Alternative Name
- switching B cell complex subunit SWAP70
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Background
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Synonyms: switching B cell complex subunit SWAP70 , HSPC321 , SWAP-70
Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
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Molecular Weight
- 69 kDa
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Gene ID
- 23075
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UniProt
- Q9UH65
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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