TMPRSS2 antibody

Catalog No. ABIN7469634

This Rabbit Polyclonal antibody specifically detects TMPRSS2 in WB, ICC, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for TMPRSS2 antibody (ABIN7469634)

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TMPRSS2 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TMPRSS2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: LNCap

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TMPRSS2

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Alternative Name: TMPRSS2

Background:

Synonyms: transmembrane serine protease 2 , PP9284 , PRSS10

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 54 kDa

Gene ID: 7113

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interactome