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TMPRSS2 antibody

TMPRSS2 Reactivity: Human WB, ICC, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7469634
  • Target See all TMPRSS2 Antibodies
    TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
    Reactivity
    • 28
    • 9
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 24
    • 4
    • 1
    Rabbit
    Clonality
    • 26
    • 3
    Polyclonal
    Conjugate
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMPRSS2 antibody is un-conjugated
    Application
    • 23
    • 9
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human TMPRSS2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product TMPRSS2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: LNCap

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, No Preservative
    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
    Alternative Name
    TMPRSS2 (TMPRSS2 Products)
    Background

    Synonyms: transmembrane serine protease 2 , PP9284 , PRSS10

    Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    Molecular Weight
    54 kDa
    Gene ID
    7113
    UniProt
    O15393
    Pathways
    SARS-CoV-2 Protein Interactome
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