SRD5A2 antibody (Biotin)

Catalog No. ABIN720148

Product Details anti-SRD5A2 Antibody (Biotin)

Target: SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRD5A2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: 83 % sequence similarity with 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRD5A2

Isotype: IgG

Application Details

Application Notes: WB: 1:100-1000, IHC-P: 1:100-500
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SRD5A2

Target: SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))

Alternative Name: Srd5a2 (SRD5A2 Products)

Synonyms: S5AR 2 antibody, 5ART2 antibody, SRD5alpha2 antibody, SRD5A2 antibody, Srd5a2 antibody, CH73-233A22.6 antibody, wu:fk70d02 antibody, zgc:109942 antibody, zgc:112208 antibody, zgc:112455 antibody, steroid 5 alpha-reductase 2 antibody, steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) antibody, 3-oxo-5-alpha-steroid 4-dehydrogenase 2 antibody, steroid-5-alpha-reductase, alpha polypeptide 2a antibody, steroid-5-alpha-reductase, alpha polypeptide 2b antibody, SRD5A2 antibody, Srd5a2 antibody, srd5a2 antibody, LOC100125532 antibody, srd5a2a antibody, srd5a2b antibody

Background:

Synonyms: 5 alpha SR2, EC, SR type 2, Steroid 5 alpha reductase 2, 3 oxo 5 alpha steroid 4 dehydrogenase 2, 3-oxo-5-alpha-steroid 4-dehydrogenase 2, 5 alpha-SR2, 5ART2, e II 5 alpha reductase, EC, MGC138457, Micropenis, included, S5A2_HUMAN, S5AR 2, SR type 2, SRD5A2, Steroid 5 alpha reductase 2, Steroid 5-alpha-reductase 2, Steroid-5-alpha-reductase, alpha polypeptide 2 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2, Type II 5-alpha reductase.

Background: Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

Gene ID: 6716

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis