PTGFRN antibody (PE)

Catalog No. ABIN7505909

Product Details anti-PTGFRN Antibody (PE)

Target: PTGFRN (Prostaglandin F2 Receptor Negative Regulator (PTGFRN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTGFRN antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Anti-Hu CD315 PE

Specificity: The mouse monoclonal antibody 1F11 recognizes an extracellular epitope of CD315, a type I transmembrane glycoprotein expressed on keratinocytes, activated monocytes, and a subset of B cells.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: HeLa cells

Clone: 1F11

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for PTGFRN

Target: PTGFRN (Prostaglandin F2 Receptor Negative Regulator (PTGFRN))

Alternative Name: CD315 (PTGFRN Products)

Synonyms: CD315 antibody, CD9P-1 antibody, EWI-F antibody, FPRP antibody, SMAP-6 antibody, 4833445A08Rik antibody, AU042434 antibody, Trim45 antibody, prostaglandin F2 receptor inhibitor antibody, prostaglandin F2 receptor negative regulator antibody, PTGFRN antibody, ptgfrn antibody, Ptgfrn antibody

Background: Prostaglandin F2 receptor inhibitor,CD315, also known as prostaglandin F2 receptor negative regulator, is an approximately 135 kDa transmembrane glycoprotein, which associates with actin cytoskeleton, and with CD9 and CD81, but not with other tetraspanins. It seems to be involved in regulation of cell polarity and motility. CD315 is expressed mainly by keratinocytes, activated monocytes, and a subset of B cells, but it can be also used for distinguishing between strongly positive colon cancer and fibrosarcoma cells, and their negative normal cell counterparts.,PF2RI, SMAP-6, PTGFRN, FPRP, EWI-F

Gene ID: 5738

UniProt: Q9P2B2