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CLEC4A antibody

CLEC4A Reactivity: Human, Non-Human Primate ELISA, FACS, ICC Host: Mouse Monoclonal 9E8 unconjugated
Catalog No. ABIN7506129
  • Target See all CLEC4A Antibodies
    CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))
    Reactivity
    • 23
    • 11
    • 3
    • 1
    Human, Non-Human Primate
    Host
    • 15
    • 8
    • 2
    Mouse
    Clonality
    • 15
    • 9
    • 1
    Monoclonal
    Conjugate
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLEC4A antibody is un-conjugated
    Application
    • 10
    • 10
    • 6
    • 2
    • 2
    • 2
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purpose
    Anti-Hu CD367 Purified
    Specificity
    The mouse monoclonal antibody 9E8 recognizes an extracellular epitope of human CD367, a type II transmembrane protein of C-lectin family, expressed mainly on antigen presenting cells.
    Purification
    Purified by protein-A affinity chromatography.
    Immunogen
    CD367 ectodomain fused with human Fc
    Clone
    9E8
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CLEC4A Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))
    Alternative Name
    CD367 (CLEC4A Products)
    Synonyms
    CLEC4A antibody, CLECSF6 antibody, DCIR antibody, DDB27 antibody, LLIR antibody, Clecsf6 antibody, Dcir1 antibody, Clec4a antibody, zinc finger protein 705A antibody, C-type lectin domain family 4 member A antibody, C-type lectin domain family 4, member A antibody, C-type lectin domain family 4, member a2 antibody, ZNF705A antibody, CLEC4A antibody, Clec4a antibody, Clec4a2 antibody
    Background
    C-type lectin domain family 4 member A,CD367 is an approximately 20-28 kDa C-type lectin with immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic part. CD367 binds in calcium-dependent manner to mannose, fucose, and weakly also to N-acetylglucosamine. It is expressed on dendritic cells, macrophages, monocytes, B cells, and neutrophils. In rheumatoid arthitis patients CD367 is expressed also on CD4+ T cells. After ligand-mediated triggering, it is internalized by clathrin-dependent endocytosis and contributes to the antigen presentation to CD8+ T cells. It may also be involved in modulation of the antigen presenting cell response.,DCIR, CLEC4A, LLIR
    Gene ID
    50856
    UniProt
    Q9UMR7
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