IFNA antibody (AA 101-189) (HRP)

Catalog No. ABIN721819

This Rabbit Polyclonal antibody specifically detects IFNA in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for IFNA antibody (AA 101-189) (HRP) (ABIN721819)

Target: IFNA (Interferon alpha (IFNA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNA antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IFNA Antibody (HRP)

Binding Specificity: AA 101-189

Specificity: This antibody will detect all 13 subtypes of Human IFN-Alpha

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFNA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IFNA

Target: IFNA (Interferon alpha (IFNA))

Alternative Name: IFN-Alpha

Background:

Synonyms: IFNA, IFN-a, IFN-_, Interferon alpha, Interferon-alpha, IFNA1, IFNA13, IFNA1/13, IFNA4: IFNA5, IFNA6, IFNA17, IFNA21, IFNA8, IFNA2, IFNA7, IFNA14, IFNA10, IFNA16, Pan Interferon alpha

Background: Interferon-_ (IFN-_, also known as IFN-alpha, IFN-a, IFNA and Interferon-alpha) is a type I interferon and exists as 13 subtypes: IFN-_ 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17 and 21. They are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. The binding of IFN-_ to its receptor initiates an anti-viral response, but also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell.

Gene ID: 3439

UniProt: P01562

Pathways: JAK-STAT Signaling, TLR Signaling, Hepatitis C, Inflammasome