Integrin beta 2 antibody

Catalog No. ABIN7539627

This Mouse Monoclonal antibody specifically detects Integrin beta 2 in FACS. It exhibits reactivity toward Human.

Quick Overview for Integrin beta 2 antibody (ABIN7539627)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: TS1-18-1-2-11

Product Details anti-Integrin beta 2 Antibody

Purpose: AF/LE Purified Anti-Human CD18 Antibody [TS1/18.1.2.11]

Specificity: Human

Purification: Protein A/G Purified

Endotoxin Level: Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.

Immunogen: Recombinant Human CD18 protein

Isotype: IgG1, kappa

Application Details

Application Notes: FCM:2 μg/mL(1x10^5-5x10^5 cells)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS.

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Background: CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.

Gene ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation