TYRO3 antibody

Catalog No. ABIN7539631

The Mouse Monoclonal anti-TYRO3 antibody is suitable to detect TYRO3 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for TYRO3 antibody (ABIN7539631)

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TYRO3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 7A10G4

Product Details anti-TYRO3 Antibody

Purpose: Tyro3 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of Tyro3 expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TYRO3

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Alternative Name: Tyro3

Background: Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98 kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.

UniProt: Q06418

Pathways: RTK Signaling