SOCS3 antibody
Quick Overview for SOCS3 antibody (ABIN7539668)
Target
See all SOCS3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- SOCS3 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human SOCS3 (AA: full(1-225)) expressed in E. Coli.
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Isotype
- IgG1
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anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibody
SOCS3 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 Reactivity: Human ELISA, IF, IHC (p) Host: Mouse Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 155-225) antibodySOCS3 Reactivity: Mouse, Rat ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-224) antibodySOCS3 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) antibodySOCS3 Reactivity: Human WB Host: Mouse Monoclonal SO1 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-226) antibodySOCS3 Reactivity: Human ELISA Host: Mouse Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 71-85), (Middle Region) antibodySOCS3 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
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Alternative Name
- SOCS3
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Background
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
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Molecular Weight
- 24.8 kDa
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UniProt
- O14543
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Pathways
- JAK-STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
Target
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