Prostate Specific Antigen antibody

Catalog No. ABIN722976

This anti-Prostate Specific Antigen antibody is a Mouse Monoclonal antibody detecting Prostate Specific Antigen in WB, IHC (p) and IF (p). Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for Prostate Specific Antigen antibody (ABIN722976)

Target: Prostate Specific Antigen (PSA)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prostate Specific Antigen antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: PA5

Product Details anti-Prostate Specific Antigen Antibody

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: Full length native protein purified from human

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-Prostate Specific Antigen antibody (ABIN722976)

Zhou, He, Zhang, Sun, Zou: "Spectrum-based and color-selective electrochemiluminescence immunoassay for determining human prostate specific antigen in near-infrared region." in: Talanta, Vol. 165, pp. 117-121, (2017) (PubMed).

Zhu, Dai, Han, He, Mo, Chen, Chen, Wu, Yang, Jiang, Chen, Sun, Zhong: "Expression of SOCSs in human prostate cancer and their association in prognosis." in: Molecular and cellular biochemistry, Vol. 381, Issue 1-2, pp. 51-9, (2013) (PubMed).

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: PSA

Background:

Synonyms: APS, PSA, hK3, KLK2A1, Prostate-specific antigen, Gamma-seminoprotein, Seminin, Kallikrein-3, P-3 antigen, Semenogelase, KLK3

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Gene ID: 354

UniProt: P07288

Pathways: Complement System