CD226 antibody (FITC)

Catalog No. ABIN7566549

This anti-CD226 antibody is a Rat Monoclonal antibody detecting CD226 in FACS. Suitable for Mouse.

Quick Overview for CD226 antibody (FITC) (ABIN7566549)

Target: CD226

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD226 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: 10E5

Product Details anti-CD226 Antibody (FITC)

Purpose: FITC Anti-Mouse CD226 Antibody[10E5]

Isotype: IgG2b, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Comment:

Matching Isotype Control: (ABIN7469847)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for CD226

Target: CD226

Alternative Name: CD226

Background: DNAM-1,PTA1(plateletandTcellactivationantigen1),TLISA1,LFA-1associatedMoleculePTA-1,CD226 (DNAM-1) is constitutively expressed on native CD8+ cells and on CD4+ T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40 % of inactivated CD4+ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.

Gene ID: 225825

UniProt: Q8K4F0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints