AKT 1/2/3 antibody (AA 401-479) (Cy5.5)
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- Target See all AKT 1/2/3 products
- AKT 1/2/3
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Binding Specificity
- AA 401-479
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Reactivity
- Human, Mouse, Rat, Cow, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AKT 1/2/3 antibody is conjugated to Cy5.5
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Cow, Human, Mouse, Pig, Rat
- Predicted Reactivity
- Dog,Cow,Sheep,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human AKT1
- Isotype
- IgG
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anti-AKT 1/2/3 (AA 401-479) antibody
Reactivity: Human, Mouse, Rat, Cow, Pig WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-AKT 1/2/3 (pSer473) antibodyReactivity: Human, Mouse, Rat, Cow, Chicken, Rabbit, Fish WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-AKT 1/2/3 (pSer472) antibodyReactivity: Human, Mouse, Rat WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-AKT 1/2/3 (pSer472) antibodyReactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReactivity: Human, Mouse, Rat WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr474) antibodyReactivity: Human, Mouse WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- AKT 1/2/3
- Alternative Name
- AKT1/2/3 (AKT 1/2/3 Products)
- Background
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Synonyms: AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, Protein kinase B, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, RAC-gamma serine/threonine-protein kinase, Protein kinase Akt-3, Protein kinase B gamma, PKB gamma, RAC-PK-gamma, STK-2, PKBG
Background: AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility, prohibitin (PHB), playing an important role in cell metabolism and proliferation, and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.
- Gene ID
- 207
- UniProt
- P31749
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