PARP2 antibody (AA 233-583)

Catalog No. ABIN7596081

Product Details anti-PARP2 Antibody

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Binding Specificity: AA 233-583

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PARP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: Human PARP2 antibody

Purification: protein-A affinity chromatography

Immunogen: Recombinant human PARP2 (233-583aa) purified from E. coli

Clone: AT29G4

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Alternative Name: PARP2 (PARP2 Products)

Background: PARP2 is poly (ADP-ribosyl) transferase-like 2 protein, which contains a catalytic domain and is capable ofcatalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to thatof poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminalcatalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of thisprotein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targetingof the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

NCBI Accession: NP_005475

Pathways: DNA Damage Repair