Annexin a1 antibody (Internal Region)

Catalog No. ABIN7598902

The Rabbit Monoclonal anti-Annexin a1 antibody (Clone N23-I) (ABIN7598902) specifically detects Annexin a1 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Annexin a1 antibody (Internal Region) (ABIN7598902)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: N23-I

Product Details anti-Annexin a1 Antibody

Binding Specificity: AA 149-166, Internal Region

Purpose: Anti-Annexin A1

Specificity: Annexin A1

Immunogen: Peptide derived from the internal region of human Annexin A1. Antibody recognizes the epitope between Ile149 - Lys166.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: +2 °C to +8 °C

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: Annexin A1

Background: Annexin A1 (ANXA1) is a phospholipid-binding protein belonging to the annexin family. It plays a key role in the regulation of inflammation, apoptosis, cell proliferation, and membrane stability. In immunohistochemistry, Annexin A1 is used as a marker in various inflammatory, autoimmune, and neoplastic conditions. Altered expression of Annexin A1 has been observed in several cancer types, including colorectal cancer, breast carcinoma, and certain leukemias. Its expression can be associated with tumor differentiation, response to therapy, and prognosis in pathological assessment.

UniProt: P04083

Pathways: Hormone Transport