CRTC3 antibody (AA 116-619)
Quick Overview for CRTC3 antibody (AA 116-619) (ABIN7599779)
Target
See all CRTC3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 116-619
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Purpose
- Anti-CRTC3 Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-CRTC3 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human CRTC3 recombinant protein (Position: R116-L619).
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Human, Monkey Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
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Alternative Name
- CRTC3
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Background
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Background: CREB-regulated transcription coactivator 3 is a protein that in humans is encoded by the CRTC3 gene. This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Gene Full Name: CREB regulated transcription coactivator 3
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Molecular Weight
- 78 kDa
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Gene ID
- 64784
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UniProt
- Q6UUV7
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Pathways
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Target
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