RRP8 antibody (AA 199-456)

Catalog No. ABIN7600459

The Rabbit Polyclonal anti-RRP8 antibody is suitable to detect RRP8 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IF, ICC and FACS.

Quick Overview for RRP8 antibody (AA 199-456) (ABIN7600459)

Target: RRP8 (Ribosomal RNA Processing 8 (RRP8))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRP8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-RRP8 Antibody

Binding Specificity: AA 199-456

Purpose: Anti-RRP8 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RRP8 Antibody (ABIN7600459). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RRP8 recombinant protein (Position: K199-R456).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RRP8

Target: RRP8 (Ribosomal RNA Processing 8 (RRP8))

Alternative Name: RRP8

Background:

Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

Background: Ribosomal RNA-processing protein 8 is a protein that in humans is encoded by the RRP8 gene. Enables methylated histone binding activity. Involved in several processes, including cellular response to glucose starvation, intrinsic apoptotic signaling pathway by p53 class mediator, and regulation of gene expression. Located in several cellular components, including cytosol, nuclear lumen, and rDNA heterochromatin. Part of chromatin silencing complex.

Molecular Weight: 65 kDa

Gene ID: 23378

UniProt: O43159