WHSC1 antibody (AA 2-478)

Catalog No. ABIN7600503

This Rabbit Polyclonal antibody specifically detects WHSC1 in WB and ELISA. It exhibits reactivity toward Human and Monkey.

Quick Overview for WHSC1 antibody (AA 2-478) (ABIN7600503)

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WHSC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-WHSC1 Antibody

Binding Specificity: AA 2-478

Purpose: Anti-WHSC1/NSD2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-WHSC1/NSD2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Monkey.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WHSC1/NSD2 recombinant protein (Position: E2-A478).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Monkey ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Alternative Name: NSD2

Background:

Background: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4,14)(p16.3,q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Gene Full Name: nuclear receptor binding SET domain protein 2

Molecular Weight: 70 kDa, 160 kDa

Gene ID: 7468

UniProt: O96028

Pathways: SARS-CoV-2 Protein Interactome