PDE10A antibody (AA 515-779)
Quick Overview for PDE10A antibody (AA 515-779) (ABIN7601943)
Target
See all PDE10A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 515-779
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Purpose
- Anti-PDE10A Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-PDE10A Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human PDE10A recombinant protein (Position: H515-D779).
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Mouse Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Expiry Date
- 12 months
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- PDE10A (phosphodiesterase 10A (PDE10A))
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Alternative Name
- PDE10A
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Background
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Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.
Gene Full Name: phosphodiesterase 10A
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Molecular Weight
- 100 kDa
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Gene ID
- 10846
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UniProt
- Q9Y233
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Pathways
- cAMP Metabolic Process
Target
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