PPP3CA antibody

Catalog No. ABIN7604191

The Rabbit Monoclonal anti-PPP3CA antibody is suitable to detect PPP3CA in samples from Human, Mouse and Rat. It has been validated for WB, IF, FACS and ICC.

Quick Overview for PPP3CA antibody (ABIN7604191)

Target: PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PPP3CA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: ABOG-16

Product Details anti-PPP3CA Antibody

Purpose: Anti-Calcineurin A Rabbit Monoclonal Antibody

Characteristics: Anti-Calcineurin A Rabbit Monoclonal Antibody (ABIN7604191). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Calcineurin A

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ICC/IF 1:50-200
FC 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for PPP3CA

Target: PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))

Alternative Name: PPP3CA

Background:

Synonyms: Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform,3.1.3.16,CAM-PRP catalytic subunit,Calmodulin-dependent calcineurin A subunit alpha isoform,PPP3CA,CALNA, CNA,

Tissue Specificity: Expressed in adult and fetal heart, brain, liver, lung, skeletal muscle, and kidney. Also expressed in testis and placenta. Highest levels in adult brain, placenta, lung, kidney, and testis. Expressed in hormone responsive tissues, including normal and cancerous mammary, ovarian and prostate epithelium. .

Molecular Weight: 59 kDa

UniProt: Q08209

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Synaptic Membrane, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling