CHEK1 antibody

Catalog No. ABIN7604428

The Rabbit Monoclonal anti-CHEK1 antibody has been validated for WB, IF, ICC and IP. It is suitable to detect CHEK1 in samples from Human, Mouse and Rat.

Quick Overview for CHEK1 antibody (ABIN7604428)

Target: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CHEK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: AAF-3

Product Details anti-CHEK1 Antibody

Purpose: Anti-Chk1 CHEK1 Rabbit Monoclonal Antibody

Characteristics: Anti-Chk1 CHEK1 Rabbit Monoclonal Antibody (ABIN7604428). Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Chk1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ICC/IF 1:50-1:200
IP 1:30

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CHEK1

Target: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Alternative Name: CHEK1

Background:

Synonyms: Serine/threonine-protein kinase Chk1,2.7.11.1,CHK1 checkpoint homolog,Cell cycle checkpoint kinase,Checkpoint kinase-1,CHEK1,CHK1,

Tissue Specificity: Expressed ubiquitously with the most abundant expression in thymus, testis, small intestine and colon. .

Molecular Weight: 54 kDa

UniProt: O14757

Pathways: p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair