Metabotropic Glutamate Receptor 5 antibody

Catalog No. ABIN7605026

The Rabbit Monoclonal anti-Metabotropic Glutamate Receptor 5 antibody (Clone EBH-7) (ABIN7605026) specifically detects Metabotropic Glutamate Receptor 5 in WB, IHC, IF, ICC and FACS. The antibody is reactive with Rat, Human and Mouse samples.

Quick Overview for Metabotropic Glutamate Receptor 5 antibody (ABIN7605026)

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Metabotropic Glutamate Receptor 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: EBH-7

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody

Purpose: Anti-GRM5/Mglur5 Rabbit Monoclonal Antibody

Characteristics: Anti-GRM5/Mglur5 Rabbit Monoclonal Antibody (ABIN7605026). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human GRM5

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Metabotropic Glutamate Receptor 5

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Alternative Name: GRM5

Background:

Synonyms: Metabotropic glutamate receptor 5,mGluR5,GRM5,GPRC1E, MGLUR5,

Tissue Specificity: Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level). Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. .

Molecular Weight: 17 kDa

UniProt: P41594

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity