Phospholipase C gamma 1 antibody

Catalog No. ABIN7605986

The Rabbit Monoclonal anti-Phospholipase C gamma 1 antibody (Clone FAA-16) (ABIN7605986) specifically detects Phospholipase C gamma 1 in WB, IF, IP and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Phospholipase C gamma 1 antibody (ABIN7605986)

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Phospholipase C gamma 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: FAA-16

Product Details anti-Phospholipase C gamma 1 Antibody

Purpose: Anti-PLCG1/Plc Gamma 1 Rabbit Monoclonal Antibody

Characteristics: Anti-PLCG1/Plc Gamma 1 Rabbit Monoclonal Antibody (ABIN7605986). Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human PLCG1

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ICC/IF 1:50-200
IP 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Phospholipase C gamma 1

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Alternative Name: PLCG1

Background:

Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1,3.1.4.11,PLC-148,Phosphoinositide phospholipase C-gamma-1,Phospholipase C-II,PLC-II,Phospholipase C-gamma-1,PLC-gamma-1,PLCG1,PLC1,

Tissue Specificity: Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle. .

Molecular Weight: 149 kDa

UniProt: P19174

Pathways: RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling