TRIB3 antibody
Quick Overview for TRIB3 antibody (ABIN7606576)
Target
See all TRIB3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-TRIB3 Monoclonal Antibody
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Characteristics
- Anti-TRIB3 Monoclonal Antibody. Tested in WB, IP applications. This antibody reacts with Human.
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human TRIB3 Disrupts insulin signaling by binding ly to Akt kinases and blocking their activation. May bind ly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity.
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Isotype
- IgG
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Application Notes
- WB 1:500-2000IP 1:20
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
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Alternative Name
- TRIB3
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Background
- Tribbles pseudokinase 3
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Molecular Weight
- 40 kDa
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Gene ID
- 57761
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UniProt
- Q96RU7
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Target
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