IL13 Receptor alpha 1 antibody (Biotin)

Catalog No. ABIN7851515

The Biotin-conjugated Rabbit Monoclonal anti-IL13 Receptor alpha 1 antibody (Clone DM183) (ABIN7851515) specifically detects IL13 Receptor alpha 1 in ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for IL13 Receptor alpha 1 antibody (Biotin) (ABIN7851515)

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL13 Receptor alpha 1 antibody is conjugated to Biotin

Application: ELISA, Flow Cytometry (FACS)

Clone: DM183

Product Details anti-IL13 Receptor alpha 1 Antibody (Biotin)

Purpose: Biotinylated Anti-IL13RA1 antibody(DM183), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Alternative Name: IL13RA1

Background: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

UniProt: P78552

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response