PLAT antibody (AA 485-562) (Biotin)

Catalog No. ABIN731125

This Rabbit Polyclonal antibody specifically detects PLAT in WB, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for PLAT antibody (AA 485-562) (Biotin) (ABIN731125)

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAT antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PLAT Antibody (Biotin)

Binding Specificity: AA 485-562

Purpose: TPA Polyclonal Antibody, Biotin Conjugated

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Tissue-type plasminogen activator chain B

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PLAT

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Alternative Name: TPA

Background:

Synonyms: TPA, T-PA, Tissue-type plasminogen activator, t-plasminogen activator, PLAT

Background: Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.

Gene ID: 5327

UniProt: P00750

Pathways: Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome