Recombinant HHV8 antibody

Catalog No. ABIN7655056

This Mouse Monoclonal antibody specifically detects HHV8 in IHC and IHC (fp). It exhibits reactivity toward Human Herpesvirus 8 (HHV-8).

Quick Overview for Recombinant HHV8 antibody (ABIN7655056)

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Antibody Type: Recombinant Antibody

Reactivity: Human Herpesvirus 8 (HHV-8)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HHV8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: HHV8-3606

Product Details anti-HHV8 Antibody

Purpose: Human Herpes Virus 8 (HHV8)(HHV8/3606)

Characteristics: HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8

Isotype: IgG1, kappa

Application Details

Application Notes: ELISA: For coating use Ab at 1-5 μg/mL, order Ab without BSA, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Comment:

Positive Control: Herpes simplex type 1 (HSV-1) extract or infected cells. Tissue.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for HHV8

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Alternative Name: Herpes Virus 8

Target Type: Virus

Background:

Synonyms: HHV8, Human Herpes Virus 8, Human herpesvirus 8, Kaposi's sarcoma associated herpes virus, KSHV

Gene Symbol: Not Applicable

Molecular Weight: Not Known