Calnexin antibody (AA 501-592)

Catalog No. ABIN733073

There is 1 publication for this product available. The Rabbit Polyclonal anti-Calnexin antibody is suitable to detect Calnexin in samples from Human. It has been validated for WB, FACS, IHC (p), IHC (fro), IF (p) and IF (cc).

Quick Overview for Calnexin antibody (AA 501-592) (ABIN733073)

Target: Calnexin (CANX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-Calnexin Antibody

Binding Specificity: AA 501-592

Purpose: Calnexin Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CANX

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Calnexin antibody (ABIN733073)

Correani, Di Francesco, Mignogna, Fabrizi, Leone, Giorgi, Passeri, Casata, Fumagalli, Maras, Schininà: "Plasma Membrane Protein Profiling in Beta-Amyloid-Treated Microglia Cell Line." in: Proteomics, Vol. 17, Issue 17-18, (2017) (PubMed).

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: CANX/Calnexin

Background:

Synonyms: CNX, P90, IP90, Calnexin, Major histocompatibility complex class I antigen-binding protein p88, CANX

Background: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Gene ID: 821

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis