CD22 antibody

Catalog No. ABIN7669997

The Mouse Monoclonal anti-CD22 antibody (Clone LL2) (ABIN7669997) specifically detects CD22 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD22 antibody (ABIN7669997)

Target: CD22 (CD22 Molecule (CD22))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD22 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: LL2

Product Details anti-CD22 Antibody

Purpose: Purified Anti-Human CD22 Antibody[LL2]

Purification: >98%, Protein A/G purified

Immunogen: Recombinant Human CD22 protein

Isotype: IgG2a, kappa

Application Details

Application Notes: FCM 2 μg/mL(1x10⁵-5x10⁵ cells)

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: PBS, pH 7.2. Contains 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD22

Target: CD22 (CD22 Molecule (CD22))

Alternative Name: CD22

Background: Lyb,SIGLEC2FLJ,B-cell receptor CD,T-cell surface antigen Leu,sialic acid binding Ig-like lectin,Sialic acid-binding Ig-like lectin,CD22,SIGLEC-2,SIGLEC2,B-cell receptor CD22,BL-CAM,B-lymphocyte cell adhesion molecule,CD22 antigenMGC130020,CD22 Molecule,Lyb-8,sialic acid binding Ig-like lectin 2,Sialic acid-binding Ig-like lectin 2,SIGLEC2FLJ22814,T-cell surface antigen Leu-14,Siglec-2,CD22 Molecule,B cell receptor CD22 precursor,B lymphocyte cell adhesion molecule,BL CAM,BLCAM,CD 22,CD22 antigen,CD22 protein,Lectin 2,Leu14,Lyb8,MGC130020,sialic acid binding Ig like lectin 2,Sialic acid binding immunoglobulin like lectin 2,SIGLEC 2,T cell surface antigen Leu 14,Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or Blymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.

UniProt: P20273