Integrin Alpha2b antibody

Catalog No. ABIN7670072

The Mouse Monoclonal anti-Integrin Alpha2b antibody (Clone 10E5-F0061) (ABIN7670072) specifically detects Integrin Alpha2b in FACS. The antibody is reactive with Human samples.

Quick Overview for Integrin Alpha2b antibody (ABIN7670072)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 10E5-F0061

Product Details anti-Integrin Alpha2b Antibody

Purpose: Purified Anti-Human CD41 Antibody[10E5-F0061]

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41

Background: Integrin alpha-Iib,ITGA2B,GPalpha Iib,GPIIb,Platelet membrane glycoprotein Iib,CD41,GP2B, ITGAB,CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.

UniProt: P08514

Pathways: Integrin Complex