ITGA4 antibody (APC)

Catalog No. ABIN7670223

This Rat Monoclonal antibody specifically detects ITGA4 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for ITGA4 antibody (APC) (ABIN7670223)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: DATK32

Product Details anti-ITGA4 Antibody (APC)

Purpose: APC Anti-Mouse LPAM-1 Antibody[DATK32]

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Handling Advice: Please protected from prolonged exposure to light and do not freeze.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months.

Expiry Date: 12 months

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: LPAM-1

Background: α4β7 Integrin,CD49d/β7,LPAM-1,ITGA4,ITGB7,DATK32 antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.

UniProt: P26011, Q00651

Pathways: Integrin Complex